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Intravenous Drug Use Related Complications of the Hand and Upper Extremity

Patients in respiratory failure or impending respiratory failure, or unable to secure their airway should be intubated. Any hemodynamically unstable patient should be resuscitated with intravenous access, IV fluids, placed on complications of iv drug use a cardiac monitor and if needed placed on vasopressors. Other causes of AMS or neurological abnormalities in PWID include septic emboli to CNS from endocarditis, mycotic aneurysms, and delayed leukoencephalopathy (6).

complications of iv drug use

Wound Care

It’s devastating and heartbreaking for the patient and their family, especially at such a young age. When the heart valves are damaged from the bacteria, the heart valves will likely require replacement surgery, which is an ordeal in itself. Once the patient has heart valve replacement surgery, he or she will be on anticoagulants for the rest of their life to prevent a clot from developing on the new valves.

RESULTS

Endocarditis can eventually cause a heart murmur, as well as fever, chest pains, fainting spells, shortness of breath, and heart palpitations as well as congestive heart failure. It can be treated with antibiotics or antifungal agents if detected early, but requires several weeks, or months, of IV antibiotics and/or heart valve replacement surgery if not detected early. Inadequate treatment of opioid withdrawal symptoms resulted in several participants reporting intravenous drug use while hospitalized. Opioid withdrawal symptoms while hospitalized for SBI were present among most participants. Participants reported storing cottons wet for a prolonged time in drug dilution from previous injections for a https://ecosoberhouse.com/ “cotton shot” when they did not have access to drugs.

complications of iv drug use

According to research, chronic venous disease is just one of many harmful consequences that can develop as a result of unsafe IV drug use. Phlebitis is inflammation of a vein, and infiltration is the leakage of intravenous (IV) fluids or medications into surrounding areas. At Great Oaks Recovery Center, we offer individualized treatment programs that are geared toward the individual needs of each client we serve. We can offer psycho-educational group sessions, individual therapy, group therapy, recreational activities, alcohol and drug educational groups, and more. Each element in the program is included to help the client reach his or her recovery goals.

What Illicit Drugs Are Used Intravenously?

CT is also important in the evaluation of sites such as the sacroiliac or sternoclavicular joints where plain film assessment is limited 24. Ultrasound can be used to detect the presence of an effusion and to guide aspiration 25. This method of drug administration poses significant health risks, including the potential for infections, vein damage, and overdose. Talc is a bulking agent that can be injected with IV drugs and can lead to pulmonary talcosis, in which talc particles travel to the pulmonary vasculature and interstitium and cause a granulomatous reaction (27). It can lead to acute respiratory failure, and as the disease progresses can lead to the conglomeration of micronodules into masses, emphysema, chronic respiratory failure, pulmonary hypertension, and right heart failure (27).

Treatment may be also complicated because IVDU patients with upper extremity infections may delay presentation to the ER because of other personal or social factors. A study conducted by Gonnella et al.13 found that late presentations to the hospital tend to increase the mean length of stay required, which led to increased costs per hospitalization. In a similar study performed by Chotai et al.,4 patients in the IVDU cohort tended to be smokers and unemployed, with a significant medical history for hepatitis C and other mental health disorders. To account for this, we manually reviewed patient medical records with a mention of IVDU or synonyms in any report to confirm that patients in fact presented with an upper extremity infection, and to determine the presence or absence of IV drug use. Second, this study represents the population at one academic medical center in the Northeast United States, and some results may not be generalizable to other geographic regions and metropolitan areas.

  • It is estimated that 17.8% of PWID are living with HIV and 52.3% are hepatitis C-antibody positive 6.
  • However, excessive alcohol intake can still have detrimental effects on overall health and increase the risk of hemorrhagic stroke in both men and women.
  • Gram-positive infections from Staphlococcus aureus and Streptococcus pyogenes are the most common and result from introduction of skin flora past the epidermis into deeper tissues (discussed below in Sepsis-Like Syndromes).

An addicted person may have started by smoking or taking a drug in a pill form. As they develop a dependence on it, they need to use higher quantities to experience a similar high as what they had when they first started using. To try to enhance their experience, someone with a substance abuse issue may start injecting drugs.

TEE is considered the method of choice for those with prosthetic valves and cardiac devices, due to the poor sensitivities of TTE in those scenarios (43). Thus, an EP can attempt a bedside TTE, but if signs of endocarditis are identified, an inpatient TEE will still be needed to further assess any of its complications (43). Hematogenous spread, extension of SSTI, or direct inoculation into muscle also puts PWID at risk for pyomyositis, an abscess-forming infection of skeletal muscle (34). Common locations include the deltoids, psoas, biceps, gastrocnemius, gluteals, and quadriceps (34).

Preventive Care Recommendations

PWID admitted to hospital with SBI should be treated in a marijuana addiction multidisciplinary manner with particular focus on avoidance of withdrawal symptoms to limit failure to complete treatment and potential high-risk behaviors while hospitalized. Participants reported using intravenous drugs while hospitalized and noted unsafe injection practices (e.g., needle re-use, using medically placed venous catheters) while doing so. Managing withdrawal symptoms in hospitalized PWID with SBI would ultimately decrease risky injection practices that may lead to severe complications, elopement or leaving the hospital against medical advice, as well as ensuring completion of treatment course 50. Self-treatment of abscesses by PWID is common and may lead to the development of SBI. Localized SSTI as a result of injection practices was a recurring theme and perceived to be manageable without seeking medical attention. Perceptions regarding risk, anecdotal experience with self-treatment, as well as physical factors including one’s addiction may explain reluctance to seek medical care.

A clinical study on drug-related problems associated with intravenous drug administration

CT findings are similar to those on plain radiographs and include soft tissue swelling, regional osteopenia and cortical erosions. While CT provides greater sensitivity than plain radiographs and is the imaging modality of choice for assessment of osseous erosions, it cannot reliably identify bone oedema early in the disease process 17, 18. PWID are at risk for necrotizing soft tissue infections (NSTIs) including subcutaneous tissue infection, necrotizing fasciitis, and myonecrosis (gas gangrene); these are less common, but life-threatening complications of SSTIs (34). As mentioned above, the practice of injecting into the groin or into the corpus cavernosa can lead to the NSTI Fournier’s gangrene (34,34). As such the practitioner should look for pain out of proportion to exam, hemorrhagic bullae, and crepitus, although in PWID an NSTI may masquerade as cellulitis or an abscess (34). NSTI is polymicrobial in nearly half the cases, including infections with Staphylococcal and Streptococcal species, Pseudomonas, Eikenella, Clostridium, and Prevotella species (34).

What Is Venous Insufficiency?

Some participants that visited needle exchanges received alcohol swabs as part of their drug kit although reported use was sporadic, even in those with prior personal experience of SBI. Amphetamines are sympathomimetic drugs that cause a surge in the sympathetic nervous system, leading to elevated blood pressure and vasospasm. This can result in a stroke, particularly in young and otherwise healthy people. Amphetamines can also cause direct damage to cerebral vessels, leading to vessel wall necrosis, microinfarcts, and atherosclerosis. Amphetamines are sympathomimetic drugs that increase the risk of stroke by almost four times that of non-users. Amphetamines can cause both ischemic and hemorrhagic strokes, with the latter being more common.

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